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Search Results for " Inflammatory bowel disease "

ターゲット

54

阻害剤

4

天然化合物

46

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T22437 Tazofelone LY-213829 Others
Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease.
T1752 NS6180 Potassium Channel
NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.
T4084 Sibofimloc VRT-1353385,Antibiotic-202,Antibiotic 202 Antibacterial , Antibiotic
Sibofimloc (Antibiotic-202), an antibiotic compound, is used in treating bacterial infections.
T2601 Vidofludimus SC12267,4sc-101 Dehydrogenase , DNA/RNA Synthesis , Interleukin
Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).
T64337 PF-04745637 PF4745637,PF 4745637,PF 04745637,PF-4745637 TRP/TRPV Channel
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
T17225 Vercirnon CCX282-B,GSK-1605786,Traficet-EN CCR
Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.
T19379 Ipsalazide Autophagy
Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease.
T24997 ABT-510 acetate ABT 510 acetate Apoptosis
ABT-510 acetate is an endogenous anti-angiogenic TSP peptide inhibitor, a thrombospondin analog, with anti-inflammatory, anti-cancer and anti-angiogenic activity that induces apoptosis and inhibits ovarian tumor growth i...
T28698 SC-22716 SC 22716,SC22716 Aminopeptidase
SC-22716 is an orally active leukotriene A4 (LTA4) hydrolase inhibitor.SC-22716 has potential anti-inflammatory activity and may be used in the study of inflammatory bowel disease and psoriasis.
T27138 Declopramide OXI-104,IMO-B,3-Chloroprocainamide Apoptosis
Declopramide (OXI-104) is a novel chemosensitizer with antitumor activity that induces apoptosis and can be used to study colorectal cancer and inflammatory bowel disease.
T20615 Olsalazine Dipentium,Salicylic acid Others
Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.
T5095 Oxazolone 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one Others
Oxazolone has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory...
T11179 Elubrixin SB-656933 IL Receptor , CXCR
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammat...
T11492 GSK2983559 free acid Others , RIP kinase
GSK2983559 free acid is a specific and orally bioavailable inhibitor of receptor-interacting protein 2 (RIP2) kinase. It has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inf...
T4319 Hispidol (Z)-Hispidol TNF
Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 μM.
T79600 Zharp2-1 RIP kinase
Zharp2-1, a RIPK2 inhibitor, inhibits the transcription of inflammatory cytokines induced by MDP-induced or Listeria monocytogenes infection and alleviates MDP-induced peritonitis symptoms in mice, which can be used for ...
T9975 GPR183 3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide Others
GPR183 (3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide) is a chemotactic receptor known for its role in the maturation of B cells, and the endogenous ligand is the oxysterol 7α,25-dihydroxycholes...
T10865 Cot inhibitor-1 TNF , MAPK
Cot inhibitor-1 is a selective inhibitor of Cot protein kinase (also known as Tpl2 or MAP3K8) (IC50 at 28 nM). Cot inhibitor-1 inhibited TNF-alpha production in human whole blood with IC50 of 5.7 nM. Cot is involved in a...
T21967 MEG hemisulfate Mercaptoethylguanidine hemisulfate NOS
MEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 μM for iNOS, 110 μM for ecNOS, and 60 μM for bNOS i...
T13647 Dextran sulfate sodium salt (MW 4500-5500) DSS,Dextran sulfate sodium salt (MW 4500-5500) Apoptosis , HIV Protease
Dextran sulfate sodium salt (MW 4500-5500) is an anhydrous glucose polymer with a molecular weight range of 4500-5500. Dextran sulfate sodium salt (MW 4500-5500) inhibits human immunodeficiency virus replication by preve...
T34276 Recoflavone DA 6034,DA6034,DA-6034
Recflavone( DA-6034) is a synthetic derivative of eupatilin and flavonoids that have anti-inflammatory effects against inflammatory bowel disease.
T34126 Prednisolone sodium metazoate
Prednisolone sodium metazoate is used in the treatment of Inflammatory Bowel Disease, Ulcerative Colitis, and GI Disorders.
T11140 E6130 CXCR
E6130 may be effective in the treatment of inflammatory bowel disease and is a highly selective CX3CR1 regulator for oral administration.
T4571 Balsalazide Balsalazido Lipoxygenase , STAT , Interleukin
Balsalazide (Balsalazido) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
T38944 Tetomilast OPC-6535,Tetomilast
Tetomilast (OPC-6535) is a phosphodiesterase-4 (PDE4) inhibitor, potentially effective in treating inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD).
T62462 RORγt/DHODH-IN-2
RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).
T73005 PF-07054894
PF-07054894 is a potent antagonist of the CCR6 and a targeted G protein-coupled receptor (GPCR), useful in the research of inflammatory bowel disease.
T76274 Dolcanatide
Dolcanatide, an orally active guanylate cyclase-C (GC-C) agonist, exhibits laxative, anti-nociceptive, and anti-inflammatory properties. It is utilized in research concerning inflammatory bowel disease [1] [2].
T7749 ALB-127158
ALB-127158(a) is a potent and selective melanin concentrating hormone 1 ( MCH 1 ) receptor antagonist which may be a potential treatment for inflammatory bowel disease (IBD).
T41121 Elubrixin tosylate SB-656933 tosylate,Elubrixin tosylate
Elubrixin tosylate (SB-656933 tosylate) is a high-potency, selective, competitive, and reversible CXCR2 antagonist, as well as an antagonist of the IL-8 receptor. It effectively inhibits upregulation of neutrophil CD11b ...
T62310 CDK8-IN-5
CDK8-IN-5 is a potent inhibitor of CDK8, exhibiting an inhibitory concentration (IC 50) of 72 nM. Demonstrating anti-inflammatory properties, it achieves a 43% enhancement rate of IL-10. This compound holds potential for...
T82223 HDHODH-IN-13
hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in studying inflammatory bowel disease (IBD) [1].
T76737 Abrilumab
Abrilumab, a fully human monoclonal antibody, targets the α4β7 integrin heterodimer, selectively binding to it. This specificity makes it a potential research tool for investigating inflammatory bowel disease (IBD) [1].
T26447 A 78773 A78773,A-78773
A 78773 is a potent, selective, direct, and reversible 5-lipoxygenase inhibitor. It has activity in a variety of purified cells and in more complex biological systems such as whole blood, lung fragments, and tracheal tis...
T73034 NLRP3-IN-12
NLRP3-IN-12 is a specific inhibitor of the NLRP3 inflammasome, effectively reducing IL-1β release by targeting the NLRP3 protein, and demonstrating an IC50 of 0.45 μM. This compound is utilized in the research of inflamm...
T76935 Briakinumab
Briakinumab (ABT-874), a fully human anti-IL-12/23p40 monoclonal antibody, selectively targets and neutralizes IL-12 and IL-23. This compound is utilized in the research of various autoimmune disorders, including rheumat...
T76280 Dalazatide
Dalazatide (ShK-186) is a specific inhibitor of the Kv1.3 potassium channel, employed in researching autoimmune conditions including multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 d...
T76280L Dalazatide TFA
Dalazatide (ShK-186) TFA, a precise Kv1.3 potassium channel peptide inhibitor, is employed in researching autoimmune conditions, including multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, ty...
T76056 Glepaglutide
Glepaglutide (ZP1848), a long-acting glucagon-like peptide-2 (GLP-2) analogue, functions as a potent agonist of the GLP-2 receptor (GLP-2R), effectively reducing fecal output and enhancing intestinal absorption, while al...
T79527 BET BD2-IN-1 Epigenetic Reader Domain
BET BD2-IN-1 (compound 45) is a potent, selective inhibitor of BET BD2, exhibiting an IC50 value of 1.6 nM. It suppresses Th17 cell differentiation through the reduced activation of STAT3 and NF-κB, making it relevant in...
T76057 Glepaglutide acetate
Glepaglutide (ZP1848) acetate is a long-acting glucagon-like peptide-2 (GLP-2) analogue and a potent GLP-2 receptor (GLP-2R) agonist. It significantly reduces fecal output and enhances intestinal absorption while also mi...
T70394 Deucravacitinib HCl
Deucravacitinib HCl is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bo...
T63035 Izilendustat hydrochloride
Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase that stabilizes hypoxia-inducible factor-1 alpha (HIF-1α) and hypoxia-inducible factor-2 (HIF-2). Potential for HIF-1α-related diseases (including ...
T77154 Etrolizumab
Etrolizumab (rhuMAb Beta7), a gut-selective anti-β7 integrin monoclonal antibody, targets the β7 subunit of α4β7 and αEβ7 integrins specifically, demonstrating affinity with K i values of 18 nM for Human α4β7 and 1800 pM...
T70899 Vidofludimus hemicalcium 4sc-101 hemicalcium,SC12267 hemicalcium,4sc-101 hemicalcium ; SC12267 hemicalcium
Vidofludimus hemicalcium (4sc-101; SC12267) is an orally active compound that acts as a dihydroorotate dehydrogenase (DHODH) inhibitor and serves as a novel modulator of the farnesoid X receptor (FXR). This immunomodulat...
T62556 JAK-IN-23
JAK-IN-23 is an orally active dual JAK/STAT and NF-κB inhibitor that inhibits J AK1 (IC50: 8.9 nM), J AK2 (IC50: 15 nM), and J AK3 (IC50: 46.2 nM). JAK-IN-23 exhibits strong anti-inflammatory effects and can reduce the r...
T79385 PDE1-IN-5
PDE1-IN-5 (Compound 10c) is a selective PDE1C inhibitor with an IC50 of 15 nM, exhibiting anti-inflammatory properties through the inhibition of iNOS, TNF-α, IL-1α, IL-1β, and IL-6 expression induced by LPS. It has demon...
T35708 N-acetyl-5-Aminosalicylic Acid
N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine . It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-ac...
T73231 RR-RJW100
RR-RJW100, an enantiomer of RJW100, functions as an agonist for both nuclear receptor liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1). Among its two synthesized enantiomers, RR-RJW100 and SS-RJW100, th...
T78084 PSB 0777 ammonium hydrate Adenosine Receptor
PSB 0777 ammonium hydrate is a potent and selective adenosine A2A receptor full agonist, exhibiting K i values of 44.4 nM for rat A2A receptors and 360 nM for human A2A receptors. For rat and human A1 receptors, it shows...

Compounds

Tazofelone
T22437
Synonym: LY-213829
Target: Others
NS6180
T1752
Synonym:
Target: Potassium Channel
Sibofimloc
T4084
Synonym: VRT-1353385,Antibiotic-202,Antibiotic 202
Target: Antibacterial, Antibiotic
Vidofludimus
T2601
Synonym: SC12267,4sc-101
Target: Dehydrogenase, DNA/RNA Synthesis, Interleukin
PF-04745637
T64337
Synonym: PF4745637,PF 4745637,PF 04745637,PF-4745637
Target: TRP/TRPV Channel
Vercirnon
T17225
Synonym: CCX282-B,GSK-1605786,Traficet-EN
Target: CCR
Ipsalazide
T19379
Synonym:
Target: Autophagy
ABT-510 acetate
T24997
Synonym: ABT 510 acetate
Target: Apoptosis
SC-22716
T28698
Synonym: SC 22716,SC22716
Target: Aminopeptidase
Declopramide
T27138
Synonym: OXI-104,IMO-B,3-Chloroprocainamide
Target: Apoptosis
Olsalazine
T20615
Synonym: Dipentium,Salicylic acid
Target: Others
Oxazolone
T5095
Synonym: 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one
Target: Others
Elubrixin
T11179
Synonym: SB-656933
Target: IL Receptor, CXCR
GSK2983559 free acid
T11492
Synonym:
Target: Others, RIP kinase
Hispidol
T4319
Synonym: (Z)-Hispidol
Target: TNF
Zharp2-1
T79600
Synonym:
Target: RIP kinase
GPR183
T9975
Synonym: 3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide
Target: Others
Cot inhibitor-1
T10865
Synonym:
Target: TNF, MAPK
MEG hemisulfate
T21967
Synonym: Mercaptoethylguanidine hemisulfate
Target: NOS
Dextran sulfate sodium salt (MW 4500-5500)
T13647
Synonym: DSS,Dextran sulfate sodium salt (MW 4500-5500)
Target: Apoptosis, HIV Protease
Recoflavone
T34276
Synonym: DA 6034,DA6034,DA-6034
Target:
Prednisolone sodium metazoate
T34126
Synonym:
Target:
E6130
T11140
Synonym:
Target: CXCR
Balsalazide
T4571
Synonym: Balsalazido
Target: Lipoxygenase, STAT, Interleukin
Tetomilast
T38944
Synonym: OPC-6535,Tetomilast
Target:
RORγt/DHODH-IN-2
T62462
Synonym:
Target:
PF-07054894
T73005
Synonym:
Target:
Dolcanatide
T76274
Synonym:
Target:
ALB-127158
T7749
Synonym:
Target:
Elubrixin tosylate
T41121
Synonym: SB-656933 tosylate,Elubrixin tosylate
Target:
CDK8-IN-5
T62310
Synonym:
Target:
hDHODH-IN-13
T82223
Synonym:
Target:
Abrilumab
T76737
Synonym:
Target:
A 78773
T26447
Synonym: A78773,A-78773
Target:
NLRP3-IN-12
T73034
Synonym:
Target:
Briakinumab
T76935
Synonym:
Target:
Dalazatide
T76280
Synonym:
Target:
Dalazatide TFA
T76280L
Synonym:
Target:
Glepaglutide
T76056
Synonym:
Target:
BET BD2-IN-1
T79527
Synonym:
Target: Epigenetic Reader Domain
Glepaglutide acetate
T76057
Synonym:
Target:
Deucravacitinib HCl
T70394
Synonym:
Target:
Izilendustat hydrochloride
T63035
Synonym:
Target:
Etrolizumab
T77154
Synonym:
Target:
Vidofludimus hemicalcium
T70899
Synonym: 4sc-101 hemicalcium,SC12267 hemicalcium,4sc-101 hemicalcium ; SC12267 hemicalcium
Target:
JAK-IN-23
T62556
Synonym:
Target:
PDE1-IN-5
T79385
Synonym:
Target:
N-acetyl-5-Aminosalicylic Acid
T35708
Synonym:
Target:
RR-RJW100
T73231
Synonym:
Target:
PSB 0777 ammonium hydrate
T78084
Synonym:
Target: Adenosine Receptor
1 2
カタログ番号 製品名 別名 ターゲット
T2718 Palmatine chloride Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
T5S0802 Palmatine Berbericinine,Burasaine Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T2735 5-Acetylsalicylic acid 5-acetyl-2-hydroxybenzoic acid Others
5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) has anti-inflammatory effects and can be used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or rectum, and to maintain remission ...
T0646 5-Aminosalicylic Acid Mesalazine,5-ASA,Mesalamine NF-κB , Lipoxygenase , COX , Glutathione Peroxidase , Endogenous Metabolite , PAK , PPAR
5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-05496 IL-10R alpha/IL-10RA Protein, Mouse, Recombinant (hFc) Mouse HEK293
IL10RA (Interleukin 10 Receptor Subunit Alpha, also known as CD210) is a Protein Coding gene. The protein encoded by this gene is a receptor for interleukin 10. Two transcript variants, one protein-coding, and the other,...
TMPY-05338 IL-10R alpha/IL-10RA Protein, Human, Recombinant (His) Human HEK293
IL10RA (Interleukin 10 Receptor Subunit Alpha, also known as CD210) is a Protein Coding gene. The protein encoded by this gene is a receptor for interleukin 10. Two transcript variants, one protein-coding, and the other,...
TMPY-05274 IL-23R Protein, Human, Recombinant (His) Human HEK293
IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPY-01830 VCAM-1 Protein, Mouse, Recombinant (His) Mouse HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-02938 REG4 Protein, Rat, Recombinant (His) Rat HEK293
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be inv...
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc) Human HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPK-00631 DR3/TNFRSF25 Protein, Mouse, Recombinant (His) Mouse HEK293
TNF-like ligand 1 A (TL1A) and death receptor 3 (DR3) are a ligand-receptor pair involved in the pathogenesis of inflammatory bowel disease. Group 3 innate lymphoid cells (ILC3s) regulate intestinal immunity and highly e...
TMPY-03321 IL-10R alpha/IL-10RA Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
IL10RA (Interleukin 10 Receptor Subunit Alpha, also known as CD210) is a Protein Coding gene. The protein encoded by this gene is a receptor for interleukin 10. Two transcript variants, one protein-coding, and the other,...
TMPY-05317 IL-10R alpha/IL-10RA Protein, Rhesus, Recombinant (His) Rhesus HEK293
IL10RA (Interleukin 10 Receptor Subunit Alpha, also known as CD210) is a Protein Coding gene. The protein encoded by this gene is a receptor for interleukin 10. Two transcript variants, one protein-coding, and the other,...
TMPJ-00504 Serpin A8 Protein, Human, Recombinant (His) Human Human Cells
Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hyperten...
TMPH-01559 IL-26 Protein, Human, Recombinant (His) Human Yeast
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expre...
TMPH-01560 IL-26 Protein, Human, Recombinant (His & Trx) Human E. coli
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expre...
TMPJ-01152 MAdCAM-1 Protein, Human, Recombinant (His) Human Human Cells
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an approximately 60 kDa type 1 transmembrane glycoprotein. It is an endothelial cell adhesion molecule that belongs to the immunoglobulin (Ig) superfamily of prote...
TMPJ-01150 MAdCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an approximately 60 kDa type 1 transmembrane glycoprotein. It is an endothelial cell adhesion molecule that belongs to the immunoglobulin (Ig) superfamily of prote...
TMPJ-01151 MAdCAM-1 Protein, Human, Recombinant (hFc) Human Human Cells
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an approximately 60 kDa type 1 transmembrane glycoprotein. It is an endothelial cell adhesion molecule that belongs to the immunoglobulin (Ig) superfamily of prote...
TMPK-01137 FAM3D Protein, Human, Recombinant (hFc) Human HEK293
The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (m...
TMPY-00176 FNDC4 Protein, Human, Recombinant (mFc) Human HEK293
FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10. Analysis of binding of F...
TMPK-00055 IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to the IL-17RB/IL-17RA complex, IL-25 induces downstream signaling response...
TMPY-03085 IL-10R beta/IL-10RB Protein, Rat, Recombinant (hFc) Rat HEK293
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPY-02325 IL-10R beta/IL-10RB Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPY-02324 IL-10R beta/IL-10RB Protein, Mouse, Recombinant (hFc) Mouse HEK293
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPY-01108 IL-10R beta/IL-10RB Protein, Human, Recombinant (His & hFc) Human HEK293
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPY-01236 IL-10R beta/IL-10RB Protein, Human, Recombinant (His) Human HEK293
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPJ-00213 IL-10R beta/IL-10RB Protein, Human, Recombinant (hFc) Human Human Cells
Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10...
TMPY-03245 IL-23R Protein, Rat, Recombinant (hFc) Rat HEK293
IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPY-00155 IL-23R Protein, Rat, Recombinant (His) Rat HEK293
IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPY-03008 IL-23R Protein, Cynomolgus, Rhesus, Recombinant (hFc) Cynomolgus,Rhesus HEK293
IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPY-03281 IL-23R Protein, Human, Recombinant (hFc) Human HEK293
IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPY-03308 ADAM17 Protein, Rat, Recombinant (His) Rat HEK293
ADAM17 is a member of the ADAM protein family of disintegrins and metalloproteases. ADAM17 is ubiquitously expressed in the human colon, with increased activity in the colonic mucosa of patients with ulcerative coliti...
TMPY-00493 IL-19 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the r...
TMPY-01033 IL-32 Protein, Human, Recombinant (isoform alpha, His) Human HEK293
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw...
TMPY-03693 REG4 Protein, Human, Recombinant (hFc) Human HEK293
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be inv...
TMPY-03132 REG4 Protein, Rat, Recombinant (hFc) Rat HEK293
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be inv...
TMPY-01144 VCAM-1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-05616 VCAM-1 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-01805 REG4 Protein, Mouse, Recombinant (His) Mouse HEK293
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be inv...
TMPY-00948 VCAM-1 Protein, Human, Recombinant (His) Human HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-06916 VCAM-1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-04828 TFF3 Protein, Human, Recombinant (His) Human HEK293
Trefoil factor family (TFF) peptides are involved in the maintenance of epithelial integrity and epithelial restitution. Trefoil factor-3 (TFF3) is an estrogen-regulated gene associated with prognosis in different types ...
TMPY-03834 Fas/CD95 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. is a prototype death receptor characterized...
TMPY-01426 Fas/CD95 Protein, Mouse, Recombinant (His) Mouse HEK293
CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. is a prototype death receptor characterized...
TMPY-04282 Fas/CD95 Protein, Rat, Recombinant (hFc) Rat HEK293
CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. is a prototype death receptor characterized...
TMPY-02057 Fas/CD95 Protein, Rat, Recombinant (His) Rat HEK293
CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. is a prototype death receptor characterized...
TMPY-01704 Fas/CD95 Protein, Human, Recombinant (His) Human HEK293
CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. is a prototype death receptor characterized...
TMPY-00632 Fas/CD95 Protein, Cynomolgus, Recombinant Cynomolgus HEK293
CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. is a prototype death receptor characterized...
TMPY-00799 Fas/CD95 Protein, Human, Recombinant (hFc) Human HEK293
CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. is a prototype death receptor characterized...
IL-10R alpha/IL-10RA Protein, Mouse, Recombinant (hFc)
TMPY-05496
Species: Mouse
Expression System: HEK293
IL-10R alpha/IL-10RA Protein, Human, Recombinant (His)
TMPY-05338
Species: Human
Expression System: HEK293
IL-23R Protein, Human, Recombinant (His)
TMPY-05274
Species: Human
Expression System: HEK293
VCAM-1 Protein, Mouse, Recombinant (His)
TMPY-01830
Species: Mouse
Expression System: HEK293
REG4 Protein, Rat, Recombinant (His)
TMPY-02938
Species: Rat
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (hFc)
TMPY-00947
Species: Human
Expression System: HEK293
DR3/TNFRSF25 Protein, Mouse, Recombinant (His)
TMPK-00631
Species: Mouse
Expression System: HEK293
IL-10R alpha/IL-10RA Protein, Rhesus, Recombinant (hFc)
TMPY-03321
Species: Rhesus
Expression System: HEK293
IL-10R alpha/IL-10RA Protein, Rhesus, Recombinant (His)
TMPY-05317
Species: Rhesus
Expression System: HEK293
Serpin A8 Protein, Human, Recombinant (His)
TMPJ-00504
Species: Human
Expression System: Human Cells
IL-26 Protein, Human, Recombinant (His)
TMPH-01559
Species: Human
Expression System: Yeast
IL-26 Protein, Human, Recombinant (His & Trx)
TMPH-01560
Species: Human
Expression System: E. coli
MAdCAM-1 Protein, Human, Recombinant (His)
TMPJ-01152
Species: Human
Expression System: Human Cells
MAdCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-01150
Species: Human
Expression System: Human Cells
MAdCAM-1 Protein, Human, Recombinant (hFc)
TMPJ-01151
Species: Human
Expression System: Human Cells
FAM3D Protein, Human, Recombinant (hFc)
TMPK-01137
Species: Human
Expression System: HEK293
FNDC4 Protein, Human, Recombinant (mFc)
TMPY-00176
Species: Human
Expression System: HEK293
IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00055
Species: Human
Expression System: HEK293
IL-10R beta/IL-10RB Protein, Rat, Recombinant (hFc)
TMPY-03085
Species: Rat
Expression System: HEK293
IL-10R beta/IL-10RB Protein, Mouse, Recombinant (His)
TMPY-02325
Species: Mouse
Expression System: HEK293
IL-10R beta/IL-10RB Protein, Mouse, Recombinant (hFc)
TMPY-02324
Species: Mouse
Expression System: HEK293
IL-10R beta/IL-10RB Protein, Human, Recombinant (His & hFc)
TMPY-01108
Species: Human
Expression System: HEK293
IL-10R beta/IL-10RB Protein, Human, Recombinant (His)
TMPY-01236
Species: Human
Expression System: HEK293
IL-10R beta/IL-10RB Protein, Human, Recombinant (hFc)
TMPJ-00213
Species: Human
Expression System: Human Cells
IL-23R Protein, Rat, Recombinant (hFc)
TMPY-03245
Species: Rat
Expression System: HEK293
IL-23R Protein, Rat, Recombinant (His)
TMPY-00155
Species: Rat
Expression System: HEK293
IL-23R Protein, Cynomolgus, Rhesus, Recombinant (hFc)
TMPY-03008
Species: Cynomolgus,Rhesus
Expression System: HEK293
IL-23R Protein, Human, Recombinant (hFc)
TMPY-03281
Species: Human
Expression System: HEK293
ADAM17 Protein, Rat, Recombinant (His)
TMPY-03308
Species: Rat
Expression System: HEK293
IL-19 Protein, Human, Recombinant (His)
TMPY-00493
Species: Human
Expression System: Baculovirus-Insect Cells
IL-32 Protein, Human, Recombinant (isoform alpha, His)
TMPY-01033
Species: Human
Expression System: HEK293
REG4 Protein, Human, Recombinant (hFc)
TMPY-03693
Species: Human
Expression System: HEK293
REG4 Protein, Rat, Recombinant (hFc)
TMPY-03132
Species: Rat
Expression System: HEK293
VCAM-1 Protein, Mouse, Recombinant (His & hFc)
TMPY-01144
Species: Mouse
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05616
Species: Human
Expression System: HEK293
REG4 Protein, Mouse, Recombinant (His)
TMPY-01805
Species: Mouse
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (His)
TMPY-00948
Species: Human
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06916
Species: Human
Expression System: HEK293
TFF3 Protein, Human, Recombinant (His)
TMPY-04828
Species: Human
Expression System: HEK293
Fas/CD95 Protein, Cynomolgus, Recombinant (hFc)
TMPY-03834
Species: Cynomolgus
Expression System: HEK293
Fas/CD95 Protein, Mouse, Recombinant (His)
TMPY-01426
Species: Mouse
Expression System: HEK293
Fas/CD95 Protein, Rat, Recombinant (hFc)
TMPY-04282
Species: Rat
Expression System: HEK293
Fas/CD95 Protein, Rat, Recombinant (His)
TMPY-02057
Species: Rat
Expression System: HEK293
Fas/CD95 Protein, Human, Recombinant (His)
TMPY-01704
Species: Human
Expression System: HEK293
Fas/CD95 Protein, Cynomolgus, Recombinant
TMPY-00632
Species: Cynomolgus
Expression System: HEK293
Fas/CD95 Protein, Human, Recombinant (hFc)
TMPY-00799
Species: Human
Expression System: HEK293